A novel redox-responsive ursolic acid polymeric prodrug delivery system for osteosarcoma therapy

Ursolic acid (UA), found widely in nature, exerts effective anti-tumoral activity against various malignant tumors. However, the low water solubility and poor bioavailability of UA have greatly hindered its translation to the clinic. To overcome these drawbacks, a simple redox-sensitive UA polymeric...

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Bibliographic Details
Main Authors: Daijie Fu, Zhe Ni, Kerong Wu, Peng Cheng, Xiaofeng Ji, Guoyuan Li, Xifu Shang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Drug Delivery
Subjects:
Online Access:http://dx.doi.org/10.1080/10717544.2020.1870583