Crystal structure of the C-terminal four-helix bundle of the potassium channel KCa3.1.

KCa3.1 (also known as SK4 or IK1) is a mammalian intermediate-conductance potassium channel that plays a critical role in the activation of T cells, B cells, and mast cells, effluxing potassium ions to maintain a negative membrane potential for influxing calcium ions. KCa3.1 shares primary sequence...

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Bibliographic Details
Main Authors: Tianyang Ji, Senena Corbalán-García, Stevan R Hubbard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6023178?pdf=render