IL-25 Promotes Th2 Immunity Responses in Asthmatic Mice via Nuocytes Activation.

BACKGROUND:Interleukin-25 (IL-25) is a potent activator of type-2 immune responses, and is responsible for airway inflammation in asthma. Previous reports have shown that IL-25 expressed hyper-reactivity in an experimental mouse-model of asthma. In addition, the production of IL-13/IL-5 promoted by...

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Bibliographic Details
Main Authors: Chao Wang, Qingfa Liu, Fangfang Chen, Wenjuan Xu, Caiqing Zhang, Wei Xiao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5019461?pdf=render