Mesenchymal stem cells and the neuronal microenvironment in the area of spinal cord injury

Mesenchymal stem cells and the neuronal microenvironment in the area of spinal cord injury

Cell-based technologies are used as a therapeutic strategy in spinal cord injury (SCI). Mesenchymal stem cells (MSCs), which secrete various neurotrophic factors and cytokines, have immunomodulatory, anti-apoptotic and anti-inflammatory effects, modulate reactivity/phenotype of astrocytes and the mi...

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Bibliographic Details
Main Authors: Yana O Mukhamedshina, Olga A Gracheva, Dina M Mukhutdinova, Yurii A Chelyshev, Albert A Rizvanov
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
spinal cord injury; mesenchymal stem cells; survival; migration; Rho/ROCK/PTEN; astrocytes; microglia; myelin-forming cells; axon growth; tissue integrity
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=2;spage=227;epage=237;aulast=Mukhamedshina

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=2;spage=227;epage=237;aulast=Mukhamedshina

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