Chronic Hepatitis B Treatment Strategies Using Polymerase Inhibitor-Based Combination Therapy

Viral polymerase is an essential enzyme for the amplification of the viral genome and is one of the major targets of antiviral therapies. However, a serious concern to be solved in hepatitis B virus (HBV) infection is the difficulty of eliminating covalently closed circular (ccc) DNA. More recently,...

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Bibliographic Details
Main Authors: Eriko Ohsaki, Yadarat Suwanmanee, Keiji Ueda
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/13/9/1691