Melatonin decreases cocaine-induced locomotor activity in pinealectomized rats

Objective: Several studies have shown that the time of day regulates the reinforcing effects of cocaine. Additionally, melatonin and its MT1 and MT2 receptors have been found to participate in modulation of the reinforcing effects of such addictive drugs as cocaine. Loss of the diurnal variation in...

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Bibliographic Details
Main Authors: Susana Barbosa-Méndez, Alberto Salazar-Juárez
Format: Article
Language:English
Published: Associação Brasileira de Psiquiatria (ABP)
Series:Brazilian Journal of Psychiatry
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462020000300295&lng=en&tlng=en