Developing oncolytic Herpes simplex virus type 1 through UL39 knockout by CRISPR-Cas9
<em><strong>Objective(s):</strong></em> Oncolytic Herpes simplex virus type 1 (HSV-1) has emerged as a promising strategy for cancer therapy. However, development of novel oncolytic mutants has remained a major challenge owing to low efficiency of conventional genome editing...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Mashhad University of Medical Sciences
2020-07-01
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| Series: | Iranian Journal of Basic Medical Sciences |
| Subjects: | |
| Online Access: | http://ijbms.mums.ac.ir/article_15503_f2cf48ea378621d4d26a64f04c6feafa.pdf |