Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease

Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease

24S-hydroxycholesterol is a side-chain oxidized oxysterol formed in the brain that is continuously crossing the blood-brain barrier to reach the circulation. There may be an opposite flux of 27-hydroxycholesterol, which is formed to a lower extent in the brain than in most other organs. Here we meas...

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Bibliographic Details
Main Authors: Maura Heverin, Nenad Bogdanovic, Dieter Lütjohann, Thomas Bayer, Irina Pikuleva, Lionel Bretillon, Ulf Diczfalusy, Bengt Winblad, Ingemar Björkhem
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Lipid Research
Subjects:
cerebral cholesterol
cholesterol 24S-hydroxylase
sterol 27-hydroxylase
oxysterols
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520319350

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http://www.sciencedirect.com/science/article/pii/S0022227520319350

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