T-cell derived acetylcholine aids host defenses during enteric bacterial infection with Citrobacter rodentium.

T-cell derived acetylcholine aids host defenses during enteric bacterial infection with Citrobacter rodentium.

The regulation of mucosal immune function is critical to host protection from enteric pathogens but is incompletely understood. The nervous system and the neurotransmitter acetylcholine play an integral part in host defense against enteric bacterial pathogens. Here we report that acetylcholine produ...

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Bibliographic Details
Main Authors: Valerie T Ramirez, Dayn R Godinez, Ingrid Brust-Mascher, Eric B Nonnecke, Patricia A Castillo, Mariana Barboza Gardner, Diane Tu, Jessica A Sladek, Elaine N Miller, Carlito B Lebrilla, Charles L Bevins, Melanie G Gareau, Colin Reardon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007719

Internet

https://doi.org/10.1371/journal.ppat.1007719

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