Gold Nanocomplex Strongly Modulates the PI3K/Akt Pathway and Other Pathways in MCF-7 Breast Cancer Cell Line

Gold Nanocomplex Strongly Modulates the PI3K/Akt Pathway and Other Pathways in MCF-7 Breast Cancer Cell Line

Conjugating drugs with gold nanoparticles (GNP) is a key strategy in cancer therapy. Herein, the potential inhibition of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway, and other pathways of the MCF-7 cell-line, was investigated upon treatment with gold nanorods (GNR) conjugated with a PI3K in...

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Bibliographic Details
Main Authors: Nouf N. Mahmoud, Duaa Abuarqoub, Rand Zaza, Dima A. Sabbah, Enam A. Khalil, Rana Abu-Dahab
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
gold nanorods
PI3K inhibitor
nanocomplex
transcription factors
regulatory proteins
PI3K/Akt pathway
Online Access:https://www.mdpi.com/1422-0067/21/9/3320

Internet

https://www.mdpi.com/1422-0067/21/9/3320

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