Dysfunctional Hyperpolarization-Activated Cyclic Nucleotide-gated Ion Channels in Cardiac Diseases

Abstract Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are reverse voltage-dependent, and their activation depends on the hyperpolarization of the membrane and may be directly or indirectly regulated by the cyclic adenosine monophosphate (cAMP) or other signal-transduction casca...

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Bibliographic Details
Main Authors: Xiaoqi Zhao, Tianxiang Gu
Format: Article
Language:English
Published: Sociedade Brasileira de Cirurgia Cardiovascular
Series:Brazilian Journal of Cardiovascular Surgery
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382016000200203&lng=en&tlng=en