Polymyxins–Curcumin Combination Antimicrobial Therapy: Safety Implications and Efficacy for Infection Treatment

Polymyxins–Curcumin Combination Antimicrobial Therapy: Safety Implications and Efficacy for Infection Treatment

The emergence of antimicrobial resistance in Gram-negative bacteria poses a huge health challenge. The therapeutic use of polymyxins (i.e., colistin and polymyxin B) is commonplace due to high efficacy and limiting treatment options for multidrug-resistant Gram-negative bacterial infections. Nephrot...

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Bibliographic Details
Main Authors: Chongshan Dai, Yang Wang, Gaurav Sharma, Jianzhong Shen, Tony Velkov, Xilong Xiao
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Antioxidants
Subjects:
polymyxin B
colistin
curcumin
oxidative stress
mitochondrial dysfunction
Online Access:https://www.mdpi.com/2076-3921/9/6/506

Internet

https://www.mdpi.com/2076-3921/9/6/506

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