Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles

Abstract Background Sarcopenia causes several adverse events in elderly people. Muscle fibre atrophy and interstitial fibrosis are the main histopathological changes in sarcopenia and account for decreased muscle function. Tribbles homologue 3 (TRB3) was previously reported to exhibit age‐related ex...

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Bibliographic Details
Main Authors: Guo‐Kai Shang, Lu Han, Zhi‐Hao Wang, Ya‐Peng Liu, Sen‐Bo Yan, Wen‐Wen Sai, Di Wang, Yi‐Hui Li, Wei Zhang, Ming Zhong
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Online Access:https://doi.org/10.1002/jcsm.12560