Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress

Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress

Background: Alzheimer's disease (AD) is the leading cause of dementia. With no reliable treatment that delays or reverses the progress of AD, effective medical drugs, and interventions for AD treatment are in urgent need. Clinical success for patients thus relies on gaining a clearer understand...

Full description

Bibliographic Details
Main Authors: Dongsheng Shang, Yin Hong, Wangwang Xie, Zhigang Tu, Jun Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Neurology
Subjects:
Alzheimer's disease
neuroinflammation
interleukin-1β
senescence
astrocyte
tau
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00929/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00929/full

Similar Items