Definition of Biologically Distinct Groups of Conjunctival Melanomas According to Etiological Factors and Implications for Precision Medicine

Definition of Biologically Distinct Groups of Conjunctival Melanomas According to Etiological Factors and Implications for Precision Medicine

Conjunctival melanoma (ConjMel) is a potentially deadly ocular melanoma, originating from partially sunlight-exposed mucosa. We explored the mutational landscape of ConjMel and studied the correlation with etiological factors. We collected 47 primary ConjMel samples and performed next-generation seq...

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Bibliographic Details
Main Authors: Sophie Gardrat, Alexandre Houy, Kelly Brooks, Nathalie Cassoux, Raymond Barnhill, Stéphane Dayot, Ivan Bièche, Virginie Raynal, Sylvain Baulande, Richard Marais, Sergio Roman-Roman, Marc-Henri Stern, Manuel Rodrigues
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
conjunctival melanoma
sun exposure
nevus
primary acquired melanocytosis
<i>BRAF</i>
<i>NRAS</i>
Online Access:https://www.mdpi.com/2072-6694/13/15/3836

Internet

https://www.mdpi.com/2072-6694/13/15/3836

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