Frequency of BRCA1 and BRCA2 causative founder variants in ovarian cancer patients in South-East Poland

Frequency of BRCA1 and BRCA2 causative founder variants in ovarian cancer patients in South-East Poland

Abstract Background Causative variants in BRCA1 and BRCA2 are well-established risk factors for breast and ovarian cancer. In Poland, the causative founder variants in the BRCA1 are responsible for a significant proportion of ovarian cancer cases, however, regional differences in the frequencies of...

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Bibliographic Details
Main Authors: Tomasz Kluz, Andrzej Jasiewicz, Elżbieta Marczyk, Robert Jach, Anna Jakubowska, Jan Lubiński, Steven A. Narod, Jacek Gronwald
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
BRCA1 and BRCA2 mutation
Ovarian cancer
Poland
Online Access:http://link.springer.com/article/10.1186/s13053-018-0089-x

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http://link.springer.com/article/10.1186/s13053-018-0089-x

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