DNA sensor cGAS-mediated immune recognition

DNA sensor cGAS-mediated immune recognition

Abstract The host takes use of pattern recognition receptors (PRRs) to defend against pathogen invasion or cellular damage. Among microorganism-associated molecular patterns detected by host PRRs, nucleic acids derived from bacteria or viruses are tightly supervised, providing a fundamental mechanis...

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Bibliographic Details
Main Authors: Pengyan Xia, Shuo Wang, Pu Gao, Guangxia Gao, Zusen Fan
Format: Article
Language:English
Published: SpringerOpen 2016-09-01
Series:Protein & Cell
Subjects:
cGAS
cGAMP
innate immunity
cytosolic DNAs
DNA sensors
Online Access:http://link.springer.com/article/10.1007/s13238-016-0320-3

Internet

http://link.springer.com/article/10.1007/s13238-016-0320-3

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