The Mechanisms of Pharmacological Preconditioning of the Brain and the Comparative Efficacy of the Drugs — Direct- and Indirect-Acting Glycogen Synthase Kinase-3β Inhibitors: Experimental Study
Objective: to investigate the activity of sevoflurane, dalargin, and lithium chloride in protecting the rat brain from total ischemia/reperfusion and to define whether the GSK=3^ deposphorylation contributes to the mechanism of pharmacological preconditioning. Materials and methods. Experiments were...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
Russian Academy of Medical Sciences
2012-12-01
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Series: | Obŝaâ Reanimatologiâ |
Subjects: | |
Online Access: | https://www.reanimatology.com/rmt/article/view/175 |