Retinoic acid activates two pathways required for meiosis in mice.

Retinoic acid activates two pathways required for meiosis in mice.

In all sexually reproducing organisms, cells of the germ line must transition from mitosis to meiosis. In mice, retinoic acid (RA), the extrinsic signal for meiotic initiation, activates transcription of Stra8, which is required for meiotic DNA replication and the subsequent processes of meiotic pro...

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Bibliographic Details
Main Authors: Jana Koubova, Yueh-Chiang Hu, Tanmoy Bhattacharyya, Y Q Shirleen Soh, Mark E Gill, Mary L Goodheart, Cathryn A Hogarth, Michael D Griswold, David C Page
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4125102?pdf=render

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http://europepmc.org/articles/PMC4125102?pdf=render

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