PDX1, Neurogenin-3, and MAFA: critical transcription regulators for beta cell development and regeneration

Abstract Transcription factors regulate gene expression through binding to specific enhancer sequences. Pancreas/duodenum homeobox protein 1 (PDX1), Neurogenin-3 (NEUROG3), and V-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA) are transcription factors critical for beta cell developmen...

Full description

Bibliographic Details
Main Authors: Yaxi Zhu, Qian Liu, Zhiguang Zhou, Yasuhiro Ikeda
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-017-0694-z