Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection

Large Isoform of Mammalian Relative of DnaJ is a Major Determinant of Human Susceptibility to HIV-1 Infection

Individual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1) infection have been of interest for decades. We aimed to determine the contribution of large isoform of Mammalian DnaJ (MRJ-L), a HIV-1 Vpr-interacting cellular protein, to this natural variation. Expression of M...

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Bibliographic Details
Main Authors: Yu-Ping Chiang, Wang-Huei Sheng, Pei-Lan Shao, Ya-Hui Chi, Yi-Ming Arthur Chen, Szu-Wei Huang, Hsiu-Ming Shih, Luan-Yin Chang, Chun-Yi Lu, Shan-Chwen Chang, Chien-Ching Hung, Li-Min Huang
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:EBioMedicine
Subjects:
Human immunodeficiency virus type 1 (HIV-1)
Macrophages
Mammalian relative of DnaJ (MRJ)
Susceptibility to infection
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396414000048

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http://www.sciencedirect.com/science/article/pii/S2352396414000048

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