The LXR agonist T0901317 promotes the reverse cholesterol transport from macrophages by increasing plasma efflux potential

The LXR agonist T0901317 promotes the reverse cholesterol transport from macrophages by increasing plasma efflux potential

The liver X receptors (LXRs) have been shown to affect lipoprotein plasma profile, lipid metabolism, and reverse cholesterol transport (RCT). In the present study, we investigated whether a short-term administration of the synthetic LXR agonist T0901317 (T0) to mice may affect RCT by modulating the...

Full description

Bibliographic Details
Main Authors: Ilaria Zanotti, Francesco Potì, Matteo Pedrelli, Elda Favari, Elsa Moleri, Guido Franceschini, Laura Calabresi, Franco Bernini
Format: Article
Language:English
Published: Elsevier 2008-05-01
Series:Journal of Lipid Research
Subjects:
liver X receptor
high density lipoprotein
passive diffusion
ATP binding cassette A1
scavenger receptor class B type I
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520425829

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520425829

Similar Items