Cecropin A Modulates Tight Junction-Related Protein Expression and Enhances the Barrier Function of Porcine Intestinal Epithelial Cells by Suppressing the MEK/ERK Pathway

Cecropin A Modulates Tight Junction-Related Protein Expression and Enhances the Barrier Function of Porcine Intestinal Epithelial Cells by Suppressing the MEK/ERK Pathway

Inflammatory bowel disease (IBD) in humans and animals is associated with bacterial infection and intestinal barrier dysfunction. Cecropin A, an antimicrobial peptide, has antibacterial activity against pathogenic bacteria. However, the effect of cecropin A on intestinal barrier function and its rel...

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Bibliographic Details
Main Authors: Zhenya Zhai, Xiaojun Ni, Chenglong Jin, Wenkai Ren, Jie Li, Jinping Deng, Baichuan Deng, Yulong Yin
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
antimicrobial peptide
cecropin A
tight junction protein
MEK/ERK signaling
porcine intestinal epithelial cell
Online Access:http://www.mdpi.com/1422-0067/19/7/1941

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http://www.mdpi.com/1422-0067/19/7/1941

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