Integrative analyses of the RNA modification machinery reveal tissue- and cancer-specific signatures

Integrative analyses of the RNA modification machinery reveal tissue- and cancer-specific signatures

Abstract Background RNA modifications play central roles in cellular fate and differentiation. However, the machinery responsible for placing, removing, and recognizing more than 170 RNA modifications remains largely uncharacterized and poorly annotated, and we currently lack integrative studies tha...

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Bibliographic Details
Main Authors: Oguzhan Begik, Morghan C. Lucas, Huanle Liu, Jose Miguel Ramirez, John S. Mattick, Eva Maria Novoa
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Genome Biology
Subjects:
RNA modifications
Epitranscriptomics
Tissue specificity
Dysregulation in cancer
Online Access:http://link.springer.com/article/10.1186/s13059-020-02009-z

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http://link.springer.com/article/10.1186/s13059-020-02009-z

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