Ivacaftor Inhibits Glioblastoma Stem Cell Maintenance and Tumor Progression

Ivacaftor Inhibits Glioblastoma Stem Cell Maintenance and Tumor Progression

Glioblastoma (GBM) is the most common and malignant primary brain tumor. Glioblastoma stem cells (GSCs) not only initiate and sustain uncontrolled cell proliferation but also resistant to conventional clinical therapies including temozolomide (TMZ) dependent chemotherapy and radiotherapy, implying t...

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Bibliographic Details
Main Authors: Kun Liu, Jun Pu, Zhi Nie, Yulin Shi, Liping Jiang, Qisheng Wu, Yongbin Chen, Cuiping Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ivacaftor
glioblastoma
glioblastoma stem cell
apoptosis
stemness
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.678209/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.678209/full

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