Insulin-like growth factors: Ligands, binding proteins, and receptors

Background: The insulin-like growth factor family of ligands (IGF-I, IGF-II, and insulin), receptors (IGF-IR, M6P/IGF-IIR, and insulin receptor [IR]), and IGF-binding proteins (IGFBP-1-6) play critical roles in normal human physiology and disease states. Scope of review: Insulin and insulin receptor...

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Bibliographic Details
Main Authors: Derek LeRoith, Jeff M.P. Holly, Briony E. Forbes
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877821000909