Underlying Mechanisms of Cooperativity, Input Specificity, and Associativity of Long-Term Potentiation Through a Positive Feedback of Local Protein Synthesis

Long-term potentiation (LTP) is a specific form of activity-dependent synaptic plasticity that is a leading mechanism of learning and memory in mammals. The properties of cooperativity, input specificity, and associativity are essential for LTP; however, the underlying mechanisms are unclear. Here,...

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Bibliographic Details
Main Authors: Lijie Hao, Zhuoqin Yang, Jinzhi Lei
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Computational Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fncom.2018.00025/full