X Inactivation and Progenitor Cancer Cells
In mammals, silencing of one of the two X chromosomes is necessary to achieve dosage compensation. The 17 kb non-coding RNA called Xist triggers X inactivation. Gene silencing by Xist can only be achieved in certain contexts such as in cells of the early embryo and in certain hematopoietic progenito...
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-04-01
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| Series: | Cancers |
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| Online Access: | http://www.mdpi.com/2072-6694/3/2/2169/ |