Effect of Gold Nanoparticle on 5-Fluorouracil-Induced Experimental Oral Mucositis in Hamsters

Effect of Gold Nanoparticle on 5-Fluorouracil-Induced Experimental Oral Mucositis in Hamsters

Background: Oral mucositis (OM) is a severe inflammation of the oral mucosal cells associated with chemotherapy and/or radiotherapy-induced toxicity, resulting in epithelial ulcers and higher risk of death from sepsis. The aim of the present study was to evaluate the nanoparticle (AuNp) effect on OM...

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Bibliographic Details
Main Authors: Carmem Jane Ferreira Vilar, Susana Barbosa Ribeiro, Aurigena Antunes de Araújo, Gerlane Coelho Bernardo Guerra, Raimundo Fernandes de Araújo Júnior, Gerly Anne de Castro Brito, Renata Ferreira Carvalho Leitão, Daniel de Lima Pontes, Luiz Henrique Da Silva Gasparotto, Maisie Mitchele Barbosa Oliveira, Anderson Dias Viana, Wendy Marina Toscano Queiroz de Medeiros, Breno Gustavo Porfírio Bezerra, Caroline Addison Carvalho Xavier de Medeiros
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
mucositis
hamsters
5-fluorouracil
NF-κB
gold nanoparticle
Online Access:https://www.mdpi.com/1999-4923/12/4/304

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https://www.mdpi.com/1999-4923/12/4/304

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