PAX8 expression in high-grade serous ovarian cancer positively regulates attachment to ECM via Integrin β3

PAX8 expression in high-grade serous ovarian cancer positively regulates attachment to ECM via Integrin β3

Abstract Background Ovarian cancer is the third most common cause of death among gynecologic malignancies worldwide. Understanding the biology and molecular pathogenesis of ovarian epithelial tumors is key to developing improved prognostic indicators and effective therapies. We aimed to determine th...

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Bibliographic Details
Main Authors: Amata Amy Soriano, Tiziana de Cristofaro, Tina Di Palma, Serena Dotolo, Priyanka Gokulnath, Antonella Izzo, Gaetano Calì, Angelo Facchiano, Mariastella Zannini
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Cancer Cell International
Subjects:
PAX8
Ovarian cancer
Fallopian tube epithelial secretory cells
Integrins
Integrin β3
Online Access:http://link.springer.com/article/10.1186/s12935-019-1022-8

Internet

http://link.springer.com/article/10.1186/s12935-019-1022-8

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