Pulmonary endothelium-derived PD-L1 induced by the H9N2 avian influenza virus inhibits the immune response of T cells

Pulmonary endothelium-derived PD-L1 induced by the H9N2 avian influenza virus inhibits the immune response of T cells

Abstract Background The PD-1/PD-L1 pathway is an inhibitory signaling pathway that maintains the balance between the immune response and immunotolerance, and its overactivation in cancer and viral infections inhibits T cell function. The target cells of various viruses, microvascular endothelial cel...

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Bibliographic Details
Main Authors: Qian Zhang, Xiang Mu, Hong Dong, Ge Hu, Tao Zhang, Cheng He, Naila Siddique
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Virology Journal
Subjects:
PD-L1
H9N2 virus
Primary microvascular endothelial cells
T cell immune response
Online Access:http://link.springer.com/article/10.1186/s12985-020-01341-x

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http://link.springer.com/article/10.1186/s12985-020-01341-x

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