Evolution of the division of labor between genes and enzymes in the RNA world.

The RNA world is a very likely interim stage of the evolution after the first replicators and before the advent of the genetic code and translated proteins. Ribozymes are known to be able to catalyze many reaction types, including cofactor-aided metabolic transformations. In a metabolically complex...

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Bibliographic Details
Main Authors: Gergely Boza, András Szilágyi, Ádám Kun, Mauro Santos, Eörs Szathmáry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4256009?pdf=render