On inflammatory hypothesis of depression: what is the role of IL-6 in the middle of the chaos?

Abstract Many patients with major depressive disorder (MDD) are reported to have higher levels of multiple inflammatory cytokines including interleukin 6 (IL-6). Recent studies both pre-clinical and clinical have advocated for the functional role of IL-6 in development of MDD and suggested a great p...

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Bibliographic Details
Main Authors: Elnaz Roohi, Nematollah Jaafari, Farshad Hashemian
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-021-02100-7