Recombinant Haemagglutinin Derived From the Ciliated Protozoan Tetrahymena thermophila Is Protective Against Influenza Infection

Recombinant Haemagglutinin Derived From the Ciliated Protozoan Tetrahymena thermophila Is Protective Against Influenza Infection

Current influenza vaccines manufactured using eggs have considerable limitations, both in terms of scale up production and the potential impact passaging through eggs can have on the antigenicity of the vaccine virus strains. Alternative methods of manufacture are required, particularly in the conte...

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Bibliographic Details
Main Authors: Karina Jawinski, Marcus Hartmann, Charanjit Singh, Ekaterina Kinnear, David C. Busse, Annalisa Ciabattini, Fabio Fiorino, Donata Medaglini, Claudia Maria Trombetta, Emanuele Montomoli, Vanessa Contreras, Roger Le Grand, Celine Coiffier, Charlotte Primard, Bernard Verrier, John S. Tregoning
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
influena virus
protozoa
adjuvant
nanoparticle
vaccine manufacture
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02661/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02661/full

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