Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer.

The growth arrest-specific transcript 5 gene (GAS5) encodes a long noncoding RNA (lncRNA) and hosts a number of small nucleolar RNAs (snoRNAs) that have recently been implicated in multiple cellular processes and cancer. Here, we investigate the relationship between DNA damage, p53, and the GAS5 sno...

Full description

Bibliographic Details
Main Authors: Jonathan Krell, Adam E Frampton, Reza Mirnezami, Victoria Harding, Alex De Giorgio, Laura Roca Alonso, Patrizia Cohen, Silvia Ottaviani, Teresa Colombo, Jimmy Jacob, Loredana Pellegrino, Gordon Buchanan, Justin Stebbing, Leandro Castellano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4057237?pdf=render