Asymmetric one-pot transformation of isoflavones to pterocarpans and its application in phytoalexin synthesis

Concise total syntheses of 6a-hydroxypterocarpans are sought after due to their broad spectrum of bioactivities. Here, the authors report the asymmetric syntheses of several natural isoflavonoids, including (−)-glyceollin I and (−)-glyceollin II, by means of an asymmetric transfer hydrogenation (ATH...

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Bibliographic Details
Main Authors: Philipp Ciesielski, Peter Metz
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16933-y