The role of PNPLA3 and TM6SF2 polymorphisms on liver fibrosis and metabolic abnormalities in Brazilian patients with chronic hepatitis C

Abstract Background Despite the growing body of knowledge about TM6SF2 and PNPLA3 polymorphisms in non-alcoholic fatty liver disease, their influence in the spectrum of HCV liver disease is not yet fully defined. Besides that, admixed populations, such as Brazilians, were not included in most of the...

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Main Authors: Arthur Ivan N. Oliveira, Fernanda M. Malta, Patricia Momoyo Y. Zitelli, Ana Paula M. Salles, Michele S. Gomes-Gouvea, Ana Catharina S. Nastri, Joao Renato R. Pinho, Flair J. Carrilho, Claudia P. Oliveira, Maria Cássia Mendes-Corrêa, Mario G. Pessoa, Daniel F. Mazo
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Gastroenterology
Subjects:
Online Access:https://doi.org/10.1186/s12876-021-01654-3