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Core‐binding factor acute myeloid leukemia with t(8;21): Risk factors and a novel scoring system (I‐CBFit)

Core‐binding factor acute myeloid leukemia with t(8;21): Risk factors and a novel scoring system (I‐CBFit)

Abstract Background Although the prognosis of core‐binding factor (CBF) acute myeloid leukemia (AML) is better than other subtypes of AML, 30% of patients still relapse and may require allogeneic hematopoietic cell transplantation (alloHCT). However, there is no validated widely accepted scoring sys...

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Main Authors: Celalettin Ustun, Elizabeth Morgan, Erica E. M. Moodie, Sheeja Pullarkat, Cecilia Yeung, Sigurd Broesby‐Olsen, Robert Ohgami, Young Kim, Wolfgang Sperr, Hanne Vestergaard, Dong Chen, Philip M. Kluin, Michelle Dolan, Krzysztof Mrózek, David Czuchlewski, Hans‐Peter Horny, Tracy I. George, Thomas Kielsgaard Kristensen, Nam K. Ku, Cecilia Arana Yi, Michael Boe Møller, Guido Marcucci, Linda Baughn, Ana‐Iris Schiefer, J. R. Hilberink, Vinod Pullarkat, Ryan Shanley, Jessica Kohlschmidt, Janie Coulombe, Amandeep Salhotra, Lori Soma, Christina Cho, Michael A. Linden, Cem Akin, Jason Gotlib, Gregor Hoermann, Jason Hornick, Ryo Nakamura, Joachim Deeg, Clara D. Bloomfield, Daniel Weisdorf, Mark R. Litzow, Peter Valent, Gerwin Huls, Miguel‐Angel Perales, Gautam Borthakur
Format: Article
Language:English
Published: Wiley 2018-09-01
Series:Cancer Medicine
Subjects:
acute myeloid leukemia
core‐binding factor
disease‐free survival
KIT mutation
predictive value
relapse
Online Access:https://doi.org/10.1002/cam4.1733
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https://doi.org/10.1002/cam4.1733

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