JNK activation contributes to DP5 induction and apoptosis following traumatic spinal cord injury

Growing evidence suggests that cells undergo apoptosis after spinal cord injury (SCI). However, little is known about the early events that trigger apoptosis in the contused cord. The BH3-only subfamily of pro-apoptotic regulators (e.g., bim, bad, and dp5) is recognized as initiators of the apoptoti...

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Bibliographic Details
Main Authors: Ke-Jie Yin, Gyeong-Moon Kim, Jin-Moo Lee, Yong Y. He, Jan Xu, Chung Y. Hsu
Format: Article
Language:English
Published: Elsevier 2005-12-01
Series:Neurobiology of Disease
Subjects:
DP5
JNK
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105001580