Pinus densiflora extract protects human skin fibroblasts against UVB-induced photoaging by inhibiting the expression of MMPs and increasing type I procollagen expression

Pinus densiflora extract protects human skin fibroblasts against UVB-induced photoaging by inhibiting the expression of MMPs and increasing type I procollagen expression

Exposure to ultraviolet (UV) light can cause skin photoaging, which is associated with upregulation of matrix metalloproteinases (MMPs) and downregulation of collagen synthesis. It has been reported that MMPs, especially MMP-1, MMP-3 and MMP-9, decrease the elasticity of the dermis by degrading coll...

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Bibliographic Details
Main Authors: Hoe-Yune Jung, Jae-Cheon Shin, Seon-Min Park, Na-Ri Kim, Wonjung Kwak, Bo-Hwa Choi
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Toxicology Reports
Subjects:
Pinus densiflora
Matrix metalloproteinases
Photoaging
Type I procollagen
TGF-β/Smad
Anti-oxidant
UV irradiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014000730

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http://www.sciencedirect.com/science/article/pii/S2214750014000730

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