LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion

LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion

Monocyte adhesion is a crucial step in transmigration and can be induced by lipopolysaccharide (LPS). Here, we studied the role of mammalian target of rapamycin (mTOR) complexes, mTORC1 and mTORC2, and PKC in this process. We used THP-1 cells, a human monocytic cell line, to investigate monocyte adh...

Full description

Bibliographic Details
Main Authors: Marcelle C. Ribeiro, Diogo B. Peruchetti, Leandro S. Silva, João L. Silva-Filho, Mariana C. Souza, Maria das Graças Henriques, Celso Caruso-Neves, Ana Acacia S. Pinheiro
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
lipopolysaccharide
mTORC1
mTORC2
protein kinase C
phorbol ester
human acute monocytic leukemia cell line
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2018.00067/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2018.00067/full

Similar Items