The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling.

In Caenorhabditis elegans and Drosophila melanogaster, removing the germline precursor cells increases lifespan. In worms, and possibly also in flies, this lifespan extension requires the presence of somatic reproductive tissues. How the somatic gonad signals other tissues to increase lifespan is no...

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Bibliographic Details
Main Authors: Tracy M Yamawaki, Jennifer R Berman, Monika Suchanek-Kavipurapu, Mark McCormick, Marta Maria Gaglia, Seung-Jae Lee, Cynthia Kenyon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2930862?pdf=render