Synergistic effect of interleukin 1 alpha on nontypeable <it>Haemophilus influenzae</it>-induced up-regulation of human beta-defensin 2 in middle ear epithelial cells

<p>Abstract</p> <p>Background</p> <p>We recently showed that beta-defensins have antimicrobial activity against nontypeable Haemophilus influenzae (NTHi) and that interleukin 1 alpha (IL-1 alpha) up-regulates the transcription of beta-defensin 2 (DEFB4 according to new...

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Bibliographic Details
Main Authors: Park Raekil, Takeshita Tamotsu, Pan Huiqi, Lee Haa-Yung, Moon Sung-Kyun, Cha Kiweon, Andalibi Ali, Lim David J
Format: Article
Language:English
Published: BMC 2006-01-01
Series:BMC Infectious Diseases
Online Access:http://www.biomedcentral.com/1471-2334/6/12