Regulation of distinct caspase-8 functions in retinal ganglion cells and astroglia in experimental glaucoma

Retinal ganglion cells (RGCs) expanding from the retina to the brain are primary victims of neurodegeneration in glaucoma, a leading cause of blindness; however, the neighboring astroglia survive the glaucoma-related stress and promote neuroinflammation. In light of diverse functions of caspase-8 in...

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Bibliographic Details
Main Authors: Xiangjun Yang, Qun Zeng, Gülgün Tezel
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121000073