Molecular Basis for the Evolution of Species-Specific Hemoglobin Capture by Staphylococcus aureus

During infection, bacteria must steal metals, including iron, from the host tissue. Therefore, pathogenic bacteria have evolved metal acquisition systems to overcome the elaborate processes mammals use to withhold metal from pathogens. Staphylococcus aureus uses IsdB, a hemoglobin receptor, to thiev...

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Bibliographic Details
Main Authors: Jacob E. Choby, Hanna B. Buechi, Allison J. Farrand, Eric P. Skaar, Matthew F. Barber
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.01524-18