Novel HRPT2/CDC73 gene mutations and loss of expression of parafibromin in Chinese patients with clinically sporadic parathyroid carcinomas.

OBJECTIVE: It is widely recognized that the diagnosis of parathyroid carcinoma (PC) is often difficult because of the overlap of characteristics between malignant and benign parathyroid tumors, especially at an early stage. Based on the identification of tumor suppressor gene HRPT2/CDC73 and its ass...

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Bibliographic Details
Main Authors: Ou Wang, Chunyan Wang, Min Nie, Quancai Cui, Heng Guan, Yan Jiang, Mei Li, Weibo Xia, Xunwu Meng, Xiaoping Xing
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3447805?pdf=render