The role of microglia and their CX3CR1 signaling in adult neurogenesis in the olfactory bulb

The role of microglia and their CX3CR1 signaling in adult neurogenesis in the olfactory bulb

Microglia play important roles in perinatal neuro- and synapto-genesis. To test the role of microglia in these processes during adulthood, we examined the effects of microglia depletion, via treatment of mice with the CSF-1 receptor antagonist PLX5622, and abrogated neuronal-microglial communication...

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Bibliographic Details
Main Authors: Ronen Reshef, Elena Kudryavitskaya, Haran Shani-Narkiss, Batya Isaacson, Neta Rimmerman, Adi Mizrahi, Raz Yirmiya
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-12-01
Series:eLife
Subjects:
adult neruogenesis
synapses
microglia
olfactory bulb
spines
development
Online Access:https://elifesciences.org/articles/30809

Internet

https://elifesciences.org/articles/30809

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