Hypertension is a conditional factor for the development of cardiac hypertrophy in type 2 diabetic mice.

BACKGROUND: Type 2 diabetes is frequently associated with co-morbidities, including hypertension. Here we investigated if hypertension is a critical factor in myocardial remodeling and the development of cardiac dysfunction in type 2 diabetic db/db mice. METHODS: Thereto, 14-wks-old male db/db mice...

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Main Authors: Marc van Bilsen, Anneleen Daniels, Olaf Brouwers, Ben J A Janssen, Wouter J A Derks, Agnieszka E Brouns, Chantal Munts, Casper G Schalkwijk, Ger J van der Vusse, Frans A van Nieuwenhoven
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3887022?pdf=render