Increase in net activity of serine proteinases but not gelatinases after local endotoxin exposure in the peripheral airways of healthy subjects.

Increase in net activity of serine proteinases but not gelatinases after local endotoxin exposure in the peripheral airways of healthy subjects.

We tested the hypothesis that activation of the innate immune response induces an imbalance in the proteolytic homeostasis in the peripheral airways of healthy subjects, towards excess serine or gelatinase proteinase activity. During bronchoscopy, 18 healthy human subjects underwent intra-bronchial...

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Bibliographic Details
Main Authors: Margaretha E Smith, Steven Bozinovski, Carina Malmhäll, Margareta Sjöstrand, Pernilla Glader, Per Venge, Pieter S Hiemstra, Gary P Anderson, Anders Lindén, Ingemar Qvarfordt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781029?pdf=render

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http://europepmc.org/articles/PMC3781029?pdf=render

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