ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?

ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?

The scientific landscape surrounding amyotrophic lateral sclerosis (ALS) continues to shift as the number of genes associated with the disease risk and pathogenesis, and the cellular processes involved, continues to grow. Despite decades of intense research and over 50 potentially causative or disea...

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Bibliographic Details
Main Authors: Rita Mejzini, Loren L. Flynn, Ianthe L. Pitout, Sue Fletcher, Steve D. Wilton, P. Anthony Akkari
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Neuroscience
Subjects:
amyotrophic lateral sclerosis
TDP-43
FUS
missing heritability
disease mechanisms
cell models
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01310/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.01310/full

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